Upload new images. The image library for this site will open in a new window.
Upload new documents. The document library for this site will open in a new window.
Show web part zones on the page. Web parts can be added to display dynamic content such as calendars or photo galleries.
Choose between different arrangements of page sections. Page layouts can be changed even after content has been added.
Move this whole section down, swapping places with the section below it.
Check for and fix problems in the body text. Text pasted in from other sources may contain malformed HTML which the code cleaner will remove.
Accordion feature turned off, click to turn on.
Accordion featurd turned on, click to turn off.
Change the way the image is cropped for this page layout.
Cycle through size options for this image or video.
Align the media panel to the right/left in this section.
Open the image pane in this body section. Click in the image pane to select an image from the image library.
Open the video pane in this body section. Click in the video pane to embed a video. Click ? for step-by-step instructions.
Remove the image from the media panel. This does not delete the image from the library.
Remove the video from the media panel.
Psychologist Tania Roth is working with a national consortium to better understand posttraumatic stress disorder.
Tania Roth studies what happens to the brain when stress occurs early in life, seeking to pinpoint how those kinds of bad experiences can cause molecular changes to DNA.
Now, by participating in a national consortium of researchers, the assistant professor of psychology at the University of Delaware is hoping to use her expertise to contribute to a better understanding of posttraumatic stress disorder (PTSD).
"Your early-life experiences can chemically tag your DNA, and that in turn can cause changes in the activity of your genes and behavior," Roth said. "One question is: Do chemical tags on DNA produced by adverse early-life experiences make you more susceptible to developing PTSD if you experience trauma as an adult?"
PTSD has gained attention in recent years because of its rates of occurrence among soldiers who served in wars in Iraq and Afghanistan; more than 200,000 returning combat troops have been diagnosed with the disorder. But, Roth noted, many cases also occur outside the military among victims of violent crimes and survivors of serious car accidents, for example.
Draper Laboratory, a nonprofit research and development organization based in Cambridge, Mass., which created the PTSD consortium, estimates that 8 percent of Americans will suffer from the disorder at some point in their lives. The condition can lead to panic attacks, substance abuse, depression, suicide and medical problems including cardiovascular disease.
Roth is one of about 20 researchers involved in the group effort to find objective biomarkers that could be used to diagnose PTSD. Currently, the disorder is identified through patients' reports of their symptoms and experiences.
"We know from animal models that stress does change the brain, so we know there must be a way to measure it objectively," Roth said. "By looking at various biomarkers hormone levels, genes, brain imaging we hope to come up with a way to assist a psychiatrist or psychologist in making an assessment of PTSD. This wouldn't replace the clinical assessments that are done now, but it could supplement them."
Roth, who has been interested since graduate school in the effects of early-life experiences on the brain, works in the area of behavioral epigenetics, or the study of specific molecular modifications that change gene expression and produce short- and long-term effects on physiology and behavior. She uses a rodent model to investigate the relationship between environmental experiences and life-long patterns of gene expression and behavior. Roth's work focuses on DNA methylation a chemical change in the brain that is important for cell development and gene expression.
She began collaborating with David Diamond at the University of South Florida, who was researching PTSD, to investigate whether these interactions between genes and the environment play a role in the disorder. That work brought both Roth and Diamond into the Draper consortium.
"No one of us could do this alone," Diamond said. "But collaboratively, we will be able to create a solution to one of the most expensive health care problems our nation is facing in both cost and human toll."
Move this whole section up, swapping places with the section above it.